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616.6 --- Urologie --- Andrologie --- Blaaskanker --- Erectiestoornissen --- Fertiliteit (fertiliteitsstoornissen) --- Fertiliteit (man) --- Incontinentie (urineïncontinentie) --- Oncologie (nefrologie) (nierkanker) --- Prostaathypertrofie --- Prostaatkanker --- Testiskanker --- Urineweginfecties --- Urolithiasis (nierstenen, nefrolithiasis) --- 605.8 --- urologie (gez) --- 616.6 Pathology of the urogenital system. Urinary and sexual (genital) complaints --- Pathology of the urogenital system. Urinary and sexual (genital) complaints

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This new edition differs from the preceding ones in that there has been extensive revision of most chapters. Recent advances in research gained by immunohistochemical, molecular biological, and cytogenetic methods are included, as far as they are applicable for daily diagnostic work. The chapter on neoplasms, in particular, has been greatly expanded in accordance with the new WHO International Histological Classification of genital tract tumors, covering all pertinent differential diagnostic aspects. The chapter on malignant lymphomas and hematopoetic neoplasms involving the endometrium is a new contribution to this edition (F. D. , Ulm). We have revised the chapter on gestational diseases, incorpor- ing recent advances in the differential diagnosis of gestational trophoblastic tumors. New discoveries and experiences in correlating structure and function in infertility and in h- mone replacement therapy of peri- and postmenopausal patients are also included. Many new microphotographs have been added to illustrate the advances in tumor research and in immunohistochemical detection methods. We have updated the list of references including recent relevant publications. To the correspondents and consultants who have contributed valuable observations and suggestions, bringing thereby to our attention omissions in the second edition, we acknowledge our cordial thanks. We thank Dr. Wolfram Klapper, Director of the L- phom Register of the University of Kiel, for case material for making the micropho- graphic illustrations of lymphomas. The staff of Springer-Verlag has earned our gratitude for their skill in preparing this new edition.

Endometrium -- Diseases -- Atlases. --- Endometrium -- Diseases -- Cytodiagnosis -- Atlases. --- Endometrium -- Histopathology -- Atlases. --- Endometrium --- Uterine Diseases --- Cytodiagnosis --- Laboratory Techniques and Procedures --- Uterus --- Genital Diseases, Female --- Diagnosis --- Female Urogenital Diseases --- Genitalia, Female --- Genitalia --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Female Urogenital Diseases and Pregnancy Complications --- Urogenital System --- Diseases --- Anatomy --- Gynecology & Obstetrics --- Pathology --- Medicine --- Health & Biological Sciences --- Atlases --- Histopathology --- Medicine. --- Gynecology. --- Oncology. --- Pathology. --- Medicine & Public Health. --- Mucous membrane --- Oncology  . --- Tumors --- Gynaecology --- Generative organs, Female --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Gynecology .

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Because of changing patterns in health care delivery, the management of complex urological problems is increasingly taking place in hospital emergency rooms and the offices of primary care physicians, a trend that will be exacerbated by the anticipated shortage of urologists and a rapidly growing population of elderly people. In Urological Emergencies: A Practical Guide, practicing urologists summarize the optimal management of urgent and emergent urological conditions so that physicians with limited urological training can take advantage of the many recent improvements in the management of acute urological problems. Up-to-date, evidence-based descriptions of today's optimal diagnostic and therapeutic approaches cover a wide variety of conditions ranging from traumatic, infectious, and obstructive to hemorrhagic, iatrogenic, vascular, and congenital urological emergencies. The authors review the relevant pathophysiological background and epidemiology, recommend necessary diagnostic testing, and provide detailed medical, surgical, and endourological management approaches. These include advances in diagnostic testing and radiographic imaging, nonoperative treatment of acute injuries, and endoscopic and interventional techniques for obstruction, abscess, and bleeding. The chapters are organized by pathophysiology rather than organ system, so that the reader can quickly determine best-practice approaches based on the mechanism of the given disease. Comprehensive and user friendly, Urological Emergencies: A Practical Guide offers urology residents, practicing urologists, emergency medicine practitioners, trauma surgeons, and primary care providers without immediate access to urological consultation an invaluable resource ready for immediate bedside use.

Urologic Diseases --- Emergencies. --- Urogenital System --- Urological emergencies. --- diagnosis. --- injuries. --- therapy. --- Urological emergencies -- Handbooks, manuals, etc. --- Urological emergencies --- Diagnosis --- Emergencies --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disasters --- Female Urogenital Diseases --- Disease Attributes --- Male Urogenital Diseases --- Anatomy --- Public Health --- Diseases --- Environment --- Environment and Public Health --- Female Urogenital Diseases and Pregnancy Complications --- Pathologic Processes --- Pathological Conditions, Signs and Symptoms --- Health Care --- Urology & Nephrology --- Medicine --- Health & Biological Sciences --- Genitourinary emergencies --- Urinary emergencies --- Medicine. --- Urology. --- Medicine & Public Health. --- Genitourinary organs --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Medical emergencies

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The Leydig cells of the testis represent the main source of androgens. The idea of Leydig cells as endocrine cells has been the leading characteristic of this interesting cell population till now. Our studies of the last 2 decades allowed us to reveal a new important feature of Leydig cells that is their obvious similarity with structures of the central and peripheral nervous system. This includes the expression of neurohormones, neurotransmitters, neuropeptides and glial cell antigens. In this way, it became evident that in addition to the well established control by steroids and systemic hormones, important local auto- and paracrine control mechanisms of testicular functions exist. Thus, the Leydig cells represent a specialized cell population with both endocrine and neuroendocrine properties. The discovery of the neuroendocrine features of Leydig cells gave rise to the hypothesis of a potential neuroectodermal and/or neural crest origin of testicular Leydig cells. In an experimental animal model we revealed that adult Leydig cells originate by transdifferentiation from stem/progenitor cells (pericytes and smooth muscle cells), underlying the close relationship of Leydig cells with testis microvasculature. This and the supporting data from the literature provided the basis for revealing the pericytes as a common adult stem cell type of mammalian species. Distributed by the microvasculature through the entire body, the pericyte, acting as a resting early pluripotent adult stem cell, provides an ingenious system to assure the maintenance, physiological repair and regeneration of organs, each under the influence of specific local environmental factors.

Leydig cells. --- Paraneurons. --- Stem cells. --- Leydig cells --- Paraneurons --- Stem cells --- Pericytes --- Leydig Cells --- Stem Cells --- Endothelium, Vascular --- Epithelial Cells --- Cells --- Mesoderm --- Testis --- Endocrine Cells --- Genitalia, Male --- Blood Vessels --- Gonads --- Anatomy --- Endothelium --- Germ Layers --- Epithelium --- Embryonic Structures --- Genitalia --- Cardiovascular System --- Endocrine Glands --- Tissues --- Urogenital System --- Endocrine System --- Physiology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Neuroendocrine cells --- Interstitial cells of Leydig --- Leydig's cells --- Testicular interstitial cells --- Medicine. --- Endocrinology. --- Biomedicine. --- Biomedicine general. --- Neurons --- Chromaffin cells --- Internal medicine --- Hormones --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Endocrinology . --- Biomedicine, general. --- Medicine --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research

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Questo volume nasce dall’esigenza di racchiudere in un unico testo lo studio della ghiandola prostatica in tutti i suoi aspetti, dall'istologia alla diagnosi fino al trattamento, con attenzione particolare alle problematiche di interesse specialistico (radiologico, urologico, medico nucleare, radioterapeutico e oncologico). Considerando l’elevatissima incidenza delle patologie prostatiche nella popolazione maschile e l'interesse non solo specialistico, il testo è rivolto a tutti i medici che vogliano approfondire la conoscenza delle più moderne possibilità per la diagnosi e la gestione di questo tipo di malattie. In tale contesto emerge il ruolo dell’imaging RM ottenuto con tecniche morfologica e funzionali (spettroscopia, perfusione, diffusione) allo "stato dell’arte" in un completo iter diagnostico che ne prevede l’associazione con gli altri tipi di imaging (ecografia, PET-TC, ecc.). I diversi capitoli e paragrafi, supportati da un’ampia iconografia, descrivono dettagliatamente le principali indicazioni all'esecuzione dell'esame RM sia nella fase diagnostica pre-trattamento che nel follow-up in termini di risposta alla terapia. Nel testo le diverse patologie sono trattate integrando e correlando i quadri RM con i dati clinici per un completo approccio interdisciplinare: combinazione vincente per una diagnosi precoce e una terapia mirata.

Magnetic resonance imaging. --- Prostate -- Cancer. --- Prostate -- Ultrasonic imaging. --- Exocrine Glands --- Genital Diseases, Male --- Tomography --- Diagnostic Imaging --- Genitalia, Male --- Magnetic Resonance Imaging --- Prostate --- Prostatic Diseases --- Diagnostic Techniques and Procedures --- Genitalia --- Male Urogenital Diseases --- Tissues --- Diagnosis --- Diseases --- Urogenital System --- Anatomy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Radiology, MRI, Ultrasonography & Medical Physics --- Urology & Nephrology --- Health & Biological Sciences --- Diseases. --- Cancer. --- Gland, Prostate --- Glandula prostata --- Prostata --- Prostate gland --- Medicine. --- Radiology. --- Radiotherapy. --- Oncology. --- Urology. --- Medicine & Public Health. --- Imaging / Radiology. --- Diagnostic Radiology. --- Exocrine glands --- Generative organs, Male --- Radiology, Medical. --- Oncology  . --- Tumors --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Genitourinary organs --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Radiological physics --- Physics --- Radiation